![]() Current estimates indicate that oral formulations represent about 90% of the global market share of all pharmaceutical formulations intended for human use. Around 60% of established small-molecule drug products available commercially are administered via the oral route. Oral medication is the most common form of drug administration because of advantages such as convenience of drug administration via the oral route, patient preference, cost-effectiveness, and ease of large-scale manufacturing of oral dosage forms. The challenges and development aspects of pediatric formulations will also be addressed. To this end, this review will discuss the physiological, and pharmaceutical barriers influencing drug bioavailability for the oral route of administration, as well as the conventional and novel drug delivery strategies. Different pharmaceutical technologies and drug delivery systems including nanocarriers, micelles, cyclodextrins and lipid-based carriers have been explored to enhance oral drug absorption. Attempts to overcome these factors have focused on understanding the physicochemical, biochemical, metabolic and biological barriers which limit the overall drug bioavailability. Various factors govern oral drug absorption including drug solubility, mucosal permeability, and stability in the gastrointestinal tract environment. It is the most preferred route, due to its advantages, such as non-invasiveness, patient compliance and convenience of drug administration. The oral route is the most common route for drug administration. 3Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.2Nanobiotechnology Unit, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.1Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. ![]() Alqahtani 1,2*, Mohsin Kazi 1, Mohammad A.
0 Comments
What the Bible says about unconditional love.When I looked up the hebrew word (2836) it said to cling, e.e. Vines said that it was inferred in the 3 places in the Old Testament. So the definition of Agape/o must remain as "God's Love". Instead what I found was that in the Vines Dictionary the drift was that they really don't know the definition and it can really only be inferred by context. Yet I did not know that the so called definition of Agape was not "unconditional Love". I know I can do that with God, but sometimes one feels like they are going to burst (yet there is no one that you know you can confide in for fear of gossip or sounding like you are gossiping.) I signed up for your emailed 1 minute devotions as I can see from this post (that was so needed in my search for truth on the subject) that you are spot on with the Word of God that was already revealed. ![]() I have been desiring a wonderful woman of God to help me look into the Bible for answers and to make some deep confession. I sure would love for you to be my mentor right now, to be able to pick up the phone and chat with you. I prefer teaching that avoids the word altogether, but there is helpful content in these articles. Is God's Love Unconditional? He talks about the unconditional love that saves us and the conditional love that transforms us: Hope for More than Unconditional Love. He chooses to use the word, but qualifies it, noting that most people use it incorrectly. You might also read John Piper's view of unconditional love. Gospel Coalition - Why God's Love is Better than Unconditional Gospel Coalition - Does God Love Everyone the Same?īob Russell on the Myth of Unconditional Love of: Nelson's illustrated Bible dictionary. Nelson's new illustrated Bible dictionary. So He loves by His will it is His nature to love." The reason for this is that God can find nothing enjoyable about a sinner on whom His wrath still abides. But He loves with His will (John 3:16 Rom. The New Testament never speaks of God loving unbelieving human beings with emotional love or a love that expects something in return. Contrary to popular understanding, the significance of agape is not that it is an unconditional love, but that it is primarily a love of the will rather than the emotions. "AGAPE - a Greek word for love used often in the New Testament (John 13:35 1 Cor. Why are so many Christians insistent on using a word that is not found in Scripture and causes these serious misunderstandings, a word that does not accurately describe God's love?īelow are some other respected resources and Bible teachers who explain the error of the term "unconditional" better than I can: It gives the impression that God has no expectations, no rewards, and no punishments for believers. It causes many people to believe God views all sins and all levels of devotion equally. But saying it's unconditional brings confusion. God's love for believers is unfailing, eternal, perfect, and undeserved. ✔ It's illogical to say that God's love is unconditional, but admit that every gesture of His love is conditional. ✔ God's perfect love results in rewards which are based strictly on conditions. Consequences and punishments are the result of violating a condition. Commands are conditions: do the right thing and you will please God do the wrong thing and your will displease Him. ✔ God's perfect love includes justice, which is based on conditions for right and wrong. If that condition is not fulfilled, we will spend eternity in hell. ✔ The greatest offer of God's love, His offer of salvation is based on the condition that we repent and turn to Him. If that condition were not fulfilled, all men would go to hell. ![]() ✔ The greatest act of God's love is based on the condition that Christ die for our sins. ![]() Limited Edition Collections: BUYMA is proud to introduce in mid-July 2016, a BUYMA-exclusive collection of one of Japan's most internationally renowned fashion designers who is not only a regular participant of Paris Fashion Week, but also an official emblem sponsor for the 2000 Sydney Olympics. But on BUYMA, user can find that, and more. Its current summer sale includes SS16's brand name classics with up to 80% off! BUYMA's Personal Approach: Typical online shopping doesnt involve personalized multilingual customer support. BUYMA is able to offer extraordinary, discounted prices year-round. Additionally, many BUYMA Personal Shoppers have strong connections with brands, enabling them to purchase items for prices that are competitive with retail sale prices. 365 Days of Designer Sales: BUYMA Personal Shoppers purchase items at local prices, resulting in better value for top designer goods. This is to notify that BUYMA, the social shopping website operated by Enigmo Inc. Approved products and businesses will be listed on the Business Directory page of this website. Once an item is ordered, the Personal Shopper will pick it up from the third-party retailer and ship it directly to the customer. The Office of Lieutenant Governor has created a national BUY MISSOURI economic development initiative to actively promote to other states and the world the products that are grown, manufactured, processed, and/or made in Missouri. With BUYMA user can stay ahead of trends. Access to Limited Designer Goods: With an assortment of over one million internationally desired items qualified for worldwide shipment, American-based customers gain access to brands not available in this region or that havent even arrived yet to America. This huge success has led to BUYMAs global launch as well, so people in America can also enjoy exclusive access to an extensive mix of established luxury designer and contemporary everyday international fashion, cosmetics, and home/interior trend items at good prices. ![]() With over 3.2 million members - 80,000 of them registered as 'Personal Shoppers' (sellers), living in 128 different countries - and over 7,600 brands listed, BUYMA accelerated to Japans no.1 popular social shopping service. ![]() "Master" whether it's music, or film, refers to the final output, and so what fans do-whether it be for the better or worse-are still doing enough to consider it remastering.Enigmo has launched its English version of BUYMA. We all get that you prefer your 'remasters' to the original source and that's fine but you just can't compare to actual professional experts that deal. Some people believe a remaster has to do with rescanning the film at a higher resolution, but in reality."remaster" simply means altering the final look. Well, I am very satisfied with Kai 1.0 overall and watching it on Blu-ray on an HDTV makes a whole lot more difference than on a small PC monitor so it's not necessarily the same thing, Enigmo. Shop. Click to enjoy the latest deals and coupons of Buymo ZA and save up to 75 when making purchase at checkout. Lol, i quoted the word "remaster" because I knew there'd be backlash if I flat-out called it remastering. Get 5 Buymo ZA coupon codes and promo codes at CouponBirds. but the "quotes" make the thread title sound like the most passive aggressive thing ever. Really though, I know you're asking an actually serious question. They certainly put a certain amount of "technique" into their "craft". If nothing else, you can practically feel the "passion" coming from the "uploaders". I think that their "virtues" are pretty "clear". They might be a force to be reckoned with. With over 3.2 million members - 80,000 of them registered as 'Personal Shoppers', living in 128 different countries - and over 7,600 brands listed. I think Buymo is still going to grow to what they need to be, Im already impressed with their service and their quality. Enigmo has launched its English version of BUYMA. I "think" that the colors on many of them look "good", and are "exemplary" of the "best" kind of remastering "work" that you could do. I have been working with them for over a year now and I must say their service improvement is super impressive. It isn't painful unless pressed firmly or I lean on a counter or table top with my forearms. I can't move it and it feels like it's part of the bone. Fionordequester wrote:The fan "remasters"? I "suppose" I could say that they really "speak for themselves". I discovered a small (size of an almond) hard bump on the ulna of my left arm. ![]() Once in series production, the izdeliye 30 engine will have a much longer life span than other Russian engines. The izdeliye 30 is designed to be 30% lower specific weight than its AL-41F1 predecessor, and up to 18% more effective, with an estimated thrust of 107.9 kN (24,300 lbf) dry and 171.7 kN (38,600 lbf) in afterburner. The powerplant appears to be the Saturn izdeliye 30 engine which will also power the Su-57M variant. The fighter will also feature an internal weapons bay with five missiles and an autocannon. Īccording to the jet's designers, the Checkmate is designed to fly with a range of up to 3,000 km (1,864 mi), carry a payload of up 7,400 kg (16,314 lb), and reach speeds of up to Mach 1.8 to 2.0. ![]() However, ruddervators require more sophisticated flight-control systems than conventional empennages. Instead of a set of elevators and a tail separately controlling pitch and yaw, a pair of combined ruddervators fulfil both roles. Instead of a conventional empennage, the Su-75 fighter has a V-tail similar to that of Northrop YF-23. A diverterless supersonic inlet (DSI) is mechanically simple DSI can reduce cost compared to more intricate inlet designs such as Boeing F-15 and Sukhoi Su-27. The angular ventral inlet, which wraps around the lower nose section, shares features with a DSI design concept first introduced in the Boeing X-32 aircraft. The wing area appears large, which has been interpreted by correspondent David Axe to imply that Sukhoi designed the fighter to fly and engage in combat at high altitudes-40,000 ft (12,000 m) or higher. The Su-75 Checkmate has a Diverterless supersonic inlet (DSI), a v-shape tail and internal weapons bays-all features intended to reduce radar signature. ![]() On 16 August 2022, United Aircraft Corporation reported that they plan to build four prototypes of the Su-75 Checkmate, with flight tests planned for as early as 2024. The potential export sales also stalled because Russia cannot trade using U.S. Su-75 Checkmate development could be delayed due to international sanctions on Russia, and Russia could not import semiconductors and high-tech machining equipment from the European Union. On 14 November 2021, it was reported that the production of several prototypes of the Checkmate had begun at the Komsomolsk-on-Amur Aircraft Plant, where the Sukhoi Su-57 is manufactured. Īccording to the chief executive of Rostec, Sergei Chemezov, the LTS Checkmate is expected to cost US $25–30 million each. Production is forecast to be 300 planes over 15 years. The Checkmate is designed to be low cost and for export, and may compete with the Lockheed Martin F-35 Lightning II and Shenyang FC-31 aircraft of the same light to medium-weight category. The Checkmate's maiden flight was first scheduled for 2023 and then slipped to 2024, with initial deliveries planned for 2026–2027. DevelopmentĪ static mock-up was unveiled at the 2021 MAKS air show with President of Russia Vladimir Putin in attendance. The Sukhoi Design Bureau also designates the aircraft as T-75. The Sukhoi Su-75 Checkmate ( Russian: Сухой Су-75 LTS, short for Light Tactical Aircraft in Russian) is a single-engine, stealth fighter aircraft under development by Sukhoi for export and for the Russian Aerospace Forces. ![]() No Parental Pressure - It's A Play-way Learning: That's where the point lies and this is grabbed by Yulia in order to edify her daughter in various languages. She started speaking English, French, Mandarin, Arabic, Italian, German, Spanish, and Russian with ease by the age of 4 and left everyone dumbfounded.Īccording to a language study conducted by Massachusetts Institute of Technology, more than 670,000 people of different nationalities and ages suggested the best time to learn a new language - if the goal is to reach native-speaking proficiency - is by the age of 10. But Bella, the wonder kid dipped herself in learning new languages along with her native language Russian. What an average kid can do at the age of 4? Starts to speak his mother tongue (still not fluent in it though), starts reciting numbers and alphabet, rhymes and stories. This kid can be undoubtedly termed as a child prodigy, as by the time she reached the age of 4, she already started speaking 7 different languages. A Language teacher's Daughter Has Got the Natural Flair For The Linguistic Abilities:īella Devyatkina, daughter of Yulia was born in Moscow, Russia on August 3, 2012. Let's get to know more about them and this story is sure to exhilarate you. The daughter is a pro at 8 different languages and has bagged awards at a very tender age while it is her mother who is behind all this. Here we have brought before you, the story of a mother-daughter duo that is based in Russia. What if other languages also are taught in a naturally-occurring way? Is that even possible in a formal educational setting? Maybe that's a NO. Moreover, to attain the mastery of a native speaker, it takes longer. When a child is taught another language in a formal school setting, it takes years for him to pick the language up. That's why mother tongue comes to us naturally like a running river stream. A child picks up the language in a way that she even doesn't realize. Learning to speak mother tongue happens naturally. Reading and writing shall follow in the later stages. ![]() Learning the mother tongue starts with observing, listening, repeating and speaking. Give her any word and she translates it into eight different languages. ![]() Publishers use these marks when books are returned to them. Remainder Mark - A remainder mark is usually a small black line or dot written with a felt tip pen or Sharpie on the top, bottom, side page edges and sometimes on the UPC symbol on the back of the book.If excessively worn, they will be marked as "tray worn." ![]()
![]() I000: Setting numeric variable 'VC14_REDIST_28127_X86' to value 2 On the Mac client system, browse to the URL for downloading the Horizon Client installer file. The filename format is VMware-Horizon-Client- YYMM - y.y.y - xxxxxx. dmg, where YYMM is the marketing version number, y.y. I052: Condition 'NETFRAMEWORK45 >= 378389' evaluates to true. On the Download VMware Horizon Clients page, click on the drop-down arrow under. I052: Condition 'Not VersionNT64 Or VC14_REDIST_28127_X64 = 5' evaluates to false.
![]() Compared to the previous game, Dead Rising 2 is a great successor fixing a lot of the previous title’s flaws and offering a new and fresh experience for the newcomers. The game is seen from a third-person perspective, you take control of Chuck as he takes on various missions along the course of the game, you fight hordes of zombies using what you find on your way (baseball bats, axe, crowbars,etc), these weapons have a durability meter but fear not as you can craft better and stronger weapons merging weapons on the crafting table, you can also use firearms, vehicles, and explosives to kill the Zombies. Its gameplay features cars, explosions, speed, and blood. It’s an excellent way to unlock new vehicles, but in principle, this is the racer side of the game offering a standard race, Eliminator/deathmatch and Endurance option. There are two games in one here, as outside of the story mode is the Blood Race. ![]() The post-apocalyptic environment in which the game is set is overrun with zombies. Zombie Driver: Immortal Edition is a remaster of our classic title, including the original game as well as the DLC to date, all running at 60FPS. Zombie Driver: Immortal Edition, while fun, is a challenging game. After that, the device will require you to set it up. Click the file of the software after the downloading process. You only need to download the version you prefer. On trouve là un mélange entre lexcellent zombie nation (ou dans une certaine mesure, Zombie Apocalypse, qui fut le précurseur de ce genre de jeu de zombie vue du dessus, un simple arena. Even Ada Wong can be unlocked as a playable character. Step 1 Click the Free Download icon on the main interface to get the best alternative for screen recording PS3. Kennedy, Chris Redfield, Sherry Birkin, and more as playable characters. The story revolves around Chuck Greene a former motorcycle rider who is trying to survive another Zombie outbreak at a big shopping complex, with his companions Chuck must race with time to provide resources and weapons to survive this crazy world. Zombie Driver Exor Studios produced the video game Zombie Driver, which combines action, racing, top-down, survival, and single-player gameplay. The game has multiple places across the globe that the player will visit to live through this horror. Dead Rising 2 is an action-adventure sandbox game with Hack And Slash, Beat Them Up, and Horror elements, the game is part of the Dead Rising franchise and marks the second game in the series. ![]() Essure has been on the market for more than 15 years and has been successfully used by hundreds of thousands of women.Īny effort to protect and promote women’s health must be rooted in science. Our decision was not based on concerns about the safety and efficacy of Essure. In recent years, however, the demand for Essure has decreased due to a number of factors, including decreased use of permanent contraception overall, the increasing popularity of long-acting, reversible birth control options, and inaccurate or misleading publicity about the device. Since its approval, Essure has been an important option for women seeking permanent birth control, offering a less invasive alternative to tubal ligation. According to a statement provided by the company: UPDATE: Bayer announced on July 20 that it would stop the sale of Essure at the end of 2018. Angie became an activist, seeking out other women who suffered medical problems, such as Ana, a Latina mother of four, who began bleeding profusely after the Essure device was inserted. (It sterilizes women by blocking the fallopian tube). ![]() They investigate women who say they were harmed by Essure, a device that is used to provide permanent birth control. In their latest effort, “The Bleeding Edge,” Dick and Ziering explore the ramifications of medical devices that cause harm rather than do good. military cover up of the rape of soldiers in “The Invisible War” and how college campuses cover up rape crimes in “The Hunting Ground.” These Oscar-nominated truth tellers exposed closeted politicians voting against gay rights in “Outrage,” the U.S. Kirby Dick and Amy Ziering make investigative documentaries that tackle hypocrisy. The activate icon displays behind the UI name. Draftsight : Ribbon to classic yn Studio 827 subscribers Subscribe Share 5.7K views 6 years ago How to change ribbon menu to classic menu & vice versa. Click the Active column to activate the UI.In UI Profiles, select Drafting and Annotation (or another name of a ribbon-based user interface). ![]() On the Tools tab, click Customize Interface (or type Customize). ![]()
|
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |